Polyposis of the colon and pericolic masses are common intestinal complications of schistosomiasis in Egypt. The heavy ovideposition in the submucosa with resultant schistosomal granulation tissue accounts for the polyposis coli, while such heavy deposition and classical schistosomal granuloma did not show in pericolic masses. Several trials for medical treatment of schistosomal polyposis or masses had been carried out, but, unfortunately no successful outcomes were attained. So, surgery remains the only weapon at hand for treatment of colonic schistosomiasis. Because of the actual risk of colonic leakage after a one-stage colonic resections and the technical difficulties encountered in performing the anastomosis, a three-staged surgical procedure for the treatment of patients with schistosomal colorectal polyposis or masses was evaluated and the encouraging results were obtained