Forty-eight parturient mothers had received epidural analgesia for relief of labour pain. The drugs used were either xylocaine or pethidine [50 mg diluted in 10ml normal saline] . The degrees of pain relief in labour as well as mechanisms of action of the two drugs has been described. It is concluded that epidural pethidine produced pain relief during delivery without instrumentation and that pethidine still can be used whenever local analgesic is not the first choice