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  4. Pattern of iron metabolism in different types and stages of bilharzial patients

Pattern of iron metabolism in different types and stages of bilharzial patients

Authors

El Mahrouky, S. F.
J. Egypt. Med. Assoc. 1986; 69 (9-12): 435-444
Journal of the Egyptian Medical Association [The]
Journal Country: Egypt
P-ISSN: 0013-2411
MeSH Terms: Schistosomiasis / Metabolism
Broad Subjects: Communicable Diseases, ,Metabolism
Citation: S. F. El Mahrouky, Pattern of iron metabolism in different types and stages of bilharzial patients. J. Egypt. Med. Assoc. 1986; 69 (9-12): 435-444

Abstract English

Anaemia associating both urinary and intestinal schistosomiasis was studied. Data showed a marked drop in blood haemoglobin level in all groups included in this study, which was more aggravated in case of intestinal mansoniasis associated with moderate or severe liver affection and particularly in the ascitic cases. This drop in haemoglobin was associated with a concomitant drop in serum iron. The total iron binding capacity was more or less normal in cases of urinary and intestinal schistosomiasis without complications. In intestinal mansoniasis with slight liver affection, the total iron binding capacity showed slight elevation, while in moderate liver affection the total iron binding capacity was significantly increased. A marked drop was observed in case of severe liver affection and particularly in ascitic case. The percent transferrin saturation in all the cases was subnormal and was markedly diminished in case with slight or moderate liver affection. The percent transferrin saturation was near normal level in intestinal mansoniasis with severe liver affection. The rate of intestinal iron absorption was enhanced in urinary and non-complicated intestinal cases and also in those with slight liver affection, but was markedly diminished in cases with severe liver affection, particularly in ascitic group

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