The effects of analgesics in therapeutic doses on the human urothelium
PJMR-Pakistan Journal of Medical Research Journal Country: Pakistan
P-ISSN: 0030-9842 E-ISSN: N/A
MeSH Terms:
Broad Subjects: Epithelium ,Urinary Tract
Citation: Muhammad Ashraf Qamar, The effects of analgesics in therapeutic doses on the human urothelium. Pak. J. Med. Res. 1987; 26 (4): 216-8
The effects of commonly used analgesics like acetylsalicylic acid and paracetamol in therapeutic doses on the urinary tract epithelium [urothelium] of 24 healthy male volunteers, divided into two groups of 12 volunteers each, were studied by administering acetylsalicylic acid and paracetamol in doses of 300 mg and 500 mg three times a day respectively for 5 days. A control group of 12 healthy volunteers was put on pharmacologically inactive placebo tablets. A slight, but not significant, increase in the urinary excretion of epithelial cells, leucocytes and red blood cells was observed in two groups of healthy volunteers receiving analgesics in usual therapeutic doses
