An adolescent male developed chondrolysis of the hip joint follwing minor trauma. Serological studies revealed a mild increase of a2 and g globulin, evocative of a non-specific immune response.
Based on this finding, we postulate that trauma to the articular cartilage of the hip joint triggered an auto-immune reaction causing chondrolysis of the hip akin to the auto immune response to articular surface antigens believed to be responsible for chondrolysis in slipped capital femoral epiphysis. By the same token, idiopathic adolescent chondrolysis may well be the result of an immune response to articular cartilage, initiated by subclinical trauma
John Wong Chung ,
Adolescent chondrolysis of the hip,
J. Bahrain Med. Soc. 1994;
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