This study was schemed to comprehend the latest kaleidoscopic trends of bacterial resistance in neonatal pathogens against all those antibiotics commonly employed as empirical therapy in neonates.
The methodological approach included;isolation and subsequent identification of those pathogens having caused bacterial infections in neonates, application of antibiotic sensitivity testing and finally construing the conclusion depicting patterns of antibiotic resistance by various pathogens, isolated from neonatal biological samples. Antibiotic resistance patterns was evident in gram-positive as well as in gram-negative bacteria in all the eight species identified in this study. Even antibiotic drugs which are being commonly relied upon for treating multi-resistant bacterial infections, found to be in effective against many newly emerged resistant bacteria, when used alone. Resistance Antibiotics drugs against which most prominent resistance pattern emerged include;Amikacin sulphate, Linezolid, Piperacillin / Tazobactam, Amoxicillin / Clavulanic acid, Vencomycin, Cefoperazone / Sulbactam, Ceftriaxone sodium, Ciprofloxacin, Cefixime trihydrate and Imipenem. The inferred upshot suggests that antibiotic resistance is emerging fast and ever-changing phenomenon of antibiotic resistance has significantly reduced the therapeutic space to maneuver, particularly, in treating neonatal infections
Zaib Ali Shaheryar ,Zaib Ali Shaheryar ,Zaka ur Rehman ,Muhammad Zaman ,Shahid Shah ,Kashif Ur Rahman Khan ,Sajid Mahmood Khan ,Muhammad Wahab Amjad ,Maria Abdul Ghafoor Raja ,Awais Ali Zaidi ,
Antibiotic resistance pattern shown by various pathogens causing infections in neonates,
Pak. J. Pharm. Sci. 2018;
2743-2747 Views : 0