Lady Reading Hospital ; , Department of Cardiothoracic Surgery ;
Medical Forum MonthlyJournal Country: Pakistan ISSN: 1029-385X Type of Publication: Observational Study Category: Male, Middle Aged, Humans, Female, Adult, Type of Research: Clinical Keywords: Health Systems,Health Research, C-Reactive Protein ,Leukocyte Count ,Acute Disease
The objective was to calculate the sensitivity and specificity of C reactive protein and Total leukocytecount by taking histopathological diagnosis of acute appendicitis as the gold standard.
Observational study. This study was conducted in the Surgical Unit of Lady Reading Hospital, Peshawarfrom January 2014 to December 2014. The study included 50 adult patients of either gender with clinical diagnosis of acuteappendicitis. The patients were admitted through the emergency department. The decision to operate was made bythe senior surgeon on call, on the basis of clinical features. All the cases were operated within 12 hours' ofadmission. Blood samples for Total leukocyte count and C-reactive protein measurement were collected from all thepatients before surgery. Operative findings were recorded. Removed appendices were sent for histology. The datawas entered and processed on the SPSS 16 version. The patients included 32 males and 18 females. Male to female ratio was 1.8: 1. Mean age was 24 years. Frequency of negative appendicectomy was 16%. Sensitivity, specificity and positive predictive value of Totalleukocyte count were 80.5%, 62.5% and 91.8% respectively. Sensitivity, specificity and positive predictive value ofC-reactive protein were 85.7%, 75% and 94.5% respectively. In patients with histopathologically confirmed acuteappendicitis, both the TLC and C - reactive protein were found to be statistically significant. C-reactive protein and Total Leukocyte Count supplement the clinical diagnosis of acute appendicitis
Viqar Aslam ,Shabab Hussain ,Muhammad Sherose Khan ,Sajjad Muhammad Khan ,Raza Ullah ,
C-reactive protein and total leukocyte count in the diagnosis of acute appendicitis,
Med. Forum Mon. 2015;
2-5 Views : 0