Diffuse large B-cell non-Hodgkin lymphoma of the prostate presenting with urinary outlet obstruction: a case report
Rao Ram Nawal
Bansal, Megha
Raghuvanshi, Shiwanjali
Ansari, M. S.
Neyaz, Zafar
Bansal, Megha
Raghuvanshi, Shiwanjali
Ansari, M. S.
Neyaz, Zafar
Department of Pathology ;
Urology Annals Journal Country: Saudi Arabia
P-ISSN: 0974-7796 E-ISSN: 0974-7834 Type of Publication: Case Reports Category: Humans, Male, Type of Research: Clinical
Keywords: Lymphoma, Non-Hodgkin / Diagnosis
Board Subjects: Noncommunicable Diseases, Lymphoma, Large B-Cell, Diffuse ,Prostate ,Urinary Bladder Neck Obstruction ,Immunohistochemistry ,Urinary Retention ,Tomography, X-Ray Computed
Citation: Ram Nawal Rao ,Megha Bansal ,Shiwanjali Raghuvanshi ,M. S. Ansari ,Zafar Neyaz , Diffuse large B-cell non-Hodgkin lymphoma of the prostate presenting with urinary outlet obstruction: a case report, Urol. Ann. 2015; 7 (1): 100-103
LargeB-cell non-Hodgkin lymphoma involving the prostate accounts for 0.09% and 0.1% of non-Hodgkin lymphoma. We report a case of prostatic large B-cell non-Hodgkin lymphoma in a 77-year-old male with symptoms of urinary retention most probably due to benign prostate hyperplasia. He underwent multiple needle core biopsies through transrectal ultrasound of the prostate. Histopathological examination of the core biopsies revealed diffuse infiltration by atypical lymphoid cells in the prostatic stroma, which was strongly positive for leukocyte common antigen and CD20. CD3, CK, PSA, BCL2, k-light chain, Cyclin D1 and synaptophysin were negative. Histopathology and immunohistochemical profile in the case was consistent with the diagnosis of diffuse large B-cell non-Hodgkin lymphoma of the prostate
