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  4. Early onset neonatal sepsis in preterm premature rupture of membranes

Early onset neonatal sepsis in preterm premature rupture of membranes

Authors

Ashraf Muhammad Nadeem
Zia Ul Haq, Muhammad
Ashraf, Muhammad Waseem
Sajjad, Rabia
Ahmed, Farooq
Combined Military Hospital, Sialkot ; Military Hospital, Rawalpindi, Department of Medicine ; Department of Medicine

Pak. Armed Forces Med. J. 2015; 65 (2): 226-230
PAFMJ-Pakistan Armed Forces Medical Journal
Journal Country: Pakistan
P-ISSN: 0030-9648
E-ISSN: 2411-8842
Type of Publication: Journal Article
Category: Humans, Male, Female,
Type of Research: Clinical
Keywords: Sepsis
Broad Subjects: Maternal, Reproductive and Child Health, Infant, Newborn ,Fetal Membranes, Premature Rupture ,Cross-Sectional Studies ,C-Reactive Protein
Citation: Muhammad Nadeem Ashraf ,Muhammad Zia Ul Haq ,Muhammad Waseem Ashraf ,Rabia Sajjad ,Farooq Ahmed , Early onset neonatal sepsis in preterm premature rupture of membranes, Pak. Armed Forces Med. J. 2015; 65 (2): 226-230

Abstract English

To determine the frequency of early onset neonatal sepsis in newborn with various duration of preterm premature rupture of membranes [PPROM] . Cross sectional study. Neonatal Intensive Care Unit Combined Military Hospital, Lahore from November 2009 to November 2010. Neonates of singleton pregnancies complicanted by pretern premature rupture of the membranes [PPROM] with delivery between 30 and 36 weeks gestation were included in the study. The overall frequency of neonatal sepsis was calculated on clinical and serological basis. Comparison of the frequency of sepsis among groups with varying duration of rupture of membranes was done. Out of 164 babies, 84 [51.2%] were female and 80 [48.8%] were male. Mean maternal age was 23 year [range: 18-36 years] . Mean gestational age was 33 weeks [range: 30-36 weeks] . Sepsis was suspected in 41 [25%] babies on clinical grounds. C-reactive protein was raised in 36 [22%] neonates. There was statistically insignificant difference between clinical versus serological diagnosis [p=0.515] . Frequency of neonatal sepsis was significantly higher in mothers with longer duration of rupture of membrane [p< 0.001] . Frequency of neonatal sepsis was observed to be 22%. PPROM is an important risk factor for early onset neonatal sepsis

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