The present study was carried out on 28 male albino rats divided into four groups, control group and the other three groups injected with cadmium chloride and killed after 6, 24 and 48 hours.
The concentrations of iron [Fe] , magnesium [Mg] , zinc [Zn] , calcium [Ca] , sodium [Na] , potassium [K] , cadmium [Cd] were measured in livers, kidneys and testes. The results obtained through the study revealed a significant increase of Fe, Zn, Na, Ca and Cd levels and significant decrease of K and Mg levels in the liver. However, in the kidney, there was a significant increase of Fe, Zn, Na and Cd levels and a significant decrease of Ca, Mg and K levels. The concentrations of Ca, Na, Cd and Fe were increased in testes, while Mg, Zn and K were significantly decreased. Therefore, the changes in tissue concentrations of these metals may reflect the degree of organ injuries by the effect of Cd
A. A. Ghoneim ,
Effect of cadmium on essential metal concentrations in liver, kidney and testes of rats,
Bull. Alex. Fac. Med. 1994;
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