trial, 24 overweight subjects, aged 50-80 years, with type 2 diabetes, were selected. We aimed to determine the effects of non-soybean legumes consumption on oxidative stress markers such as ox-LDL [oxidative LDL] , MDA [Malonedialdehyde] and TAC [total antioxidant capacity] in type 2 diabetic patients. The subjects were randomly assigned into two groups, receiving two diets - the TLC [controls] or the TLC diet with legumes [receiving 2 servings of legumes instead of meat three days of the week in the TLC diet] . Duration of each diet was 8 weeks with a 4 week wash-out period. At the beginning and end of each dietary period, fasting plasma glucose, ox-LDL, MDA, TAC and weight were measured. After the nutritional intervention, diabetic patients, those individuals who followed the legume-based TLC diet had significant reduction in ox- LDL [-3.1 +/- 0.5 vs. -0.7 +/- 0.4; P=0.003] and MDA [-1.1 +/- 0.2 vs. -0.3 +/- 0.1; P=0.006] , but no change was observed in the TAC and BMI of the case and control groups. The legume-based TLC diet improves oxidative stress markers in diabetic patients, compared to the legume-free TLC diet