Background: Aplastic anemia [AA] is a disorder characterized by pancytopenia and injury or loss of pluripotent hematopoietic stem cells in the absence of infiltrative disease of the bone marrow.
Hepatitis-associated aplastic anemia [HAAA] is a variant of AA Aim of the study: To investigate the possible etiology responsible for the development of HAAA
Patients and methods: 42 patients were admitted to Assiut university hospital diagnosed as having AA. Data from history, physical examination and laboratory investigations, including complete blood count [CBC] , viral serology and liver function tests were collected and statistically analyzed Conclusion: HAAA is caused by variable hepatotropic and non-hepatotropic viruses. The pathogenesis of hepatitis associated aplastic anemia HAAA may be attributed to liver cell injury, disturbed liver functions and its effects on hematopoiesis
Esam A. ElBeih ,Nabila F. Ameen ,Adel HM Mekawy ,Eman M. Ibrahim ,
[Hepatitis associated aplastic anemia in relation to liver cell injury],
Assiut Med. J. 2015;
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