Anti HCV was checked using Enzyme Immuno assay [EIA] [C100-3- Abbott] in 68 patients with chronic renal failure [CRF] who were on maintenance haemodialysis and 48 patients on conservative management.
Mean age of the patients was 50 years. The duration of illness ranged from 3 months to 18 years [mean 3 years] . All patients were Hepatitis B surface antigen [HBsAg] negative. In haemodialyzed group 31 [46%] and in conservative group only 3 [6%] were Anti HCV positive. High Frequency of Anti HCV positivity in haemodialyzed group was related to period on dialysis [1 year] and number of blood transfusions [>4 units] . Patients in whom dialyzer was re-used showed 60% positivity as compared to only 17% in those with single use. Anti HCV positivity predominated in females as compared to males.42.6% vs 20.3%. Nine out of 10 patients with a history of jaundice and six out of 8 patients with raised transaminase levels were Anti HCV positive. Fifteen of 37 Anti HBC [IgG] positive cases were Anti HCV +ve
Haren Kumar ,
Hepatitis-C virus antibodies[Anti HCV]in haemodialyzed vs non-dialyzed patients,
J. Pak. Med. Assoc. 1994;
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