COVID-19 | Discover the latest peer-reviewed research articles from the Eastern Mediterranean Region
COVID-19 | Discover the latest peer-reviewed research articles from the Eastern Mediterranean Region
COVID-19 | Discover the latest publications published by WHO Regional Office for the Eastern Mediterranean
COVID-19 | Discover the latest publications published by WHO Regional Office for the Eastern Mediterranean

Virtual Health Sciences Library

  • Home
  • Search
  • Knowledge Base
  • Get a journal indexed in the Index Medicus
  • MyVHSL
  1. Home
  2. IMEMR
  3. Search Result
  4. Management of gastroesophageal reflux disease in adults

Management of gastroesophageal reflux disease in adults

Authors

Niknam Ramin
Shiraz University of Medical Sciences ; Tehran University of Medical Sciences, Gastroenterohepatology Research Center ; Digestive Disease Research Center,

Trends Pharm. Sci. 2015; 1 (2): 65-74
TIPS-Trends in Pharmaceutical Sciences
Journal Country: Islamic Republic of Iran
P-ISSN: 2423-3722
E-ISSN: 2423-5652
Indexing Status : In Process
Citation: Ramin Niknam , Management of gastroesophageal reflux disease in adults, Trends Pharm. Sci. 2015; 1 (2): 65-74

Abstract English

Gastroesophageal reflux disease [GERD] is a very common disease. GERD is defined as the reflux of stomach content which causes troublesome symptoms and/or complications. The management of GERD is step by step. Dietary and lifestyle modifications are the first steps. Twice-daily H2RAs at standard doses for a minimum duration of two weeks can be considered in patients with GERD who fail to respond to lifestyle and dietary modifications. If symptoms of GERD persist, once-daily Proton Pump Inhibitors [PPIs] can be recommended. Patients with an unsatisfactory response to once-daily PPIs dosing can be considered to have refractory GERD. Twice-daily PPI therapy can be recommended in patients who fail to respond to once-daily PPI therapy. The add-on treatment with H2RAs, baclofen, or visceral pain modulators can be considered in selective subjects with GERD who fail to respond to twice daily PPI. Anti-reflux surgery may be taken into account in selected patients. This review focuses on the initial and maintenance therapy of GERD and also reviews different management of recurrent and refractory GERD

Full Text English
1 Downloads

Subscribe to VHSL Newsletters

© 2020 WHO – EMRO