Two female siblings, the products of a first cousin marriage presented with severe hypoglycaemia in the early neonatal period. Serum insulin levels were 25.8 mlU/litre and 21.6 mlU/litre respectively.
The histology of the pancreatic glands revealed scattered areas of hypertrophied islet cells among normal cell groups with ductendocrine proliferation thus confirming a diagnosis of nesidioblastosis. This is the first case report of the disorder in Omani children and the family pedigree was in keeping with an autosomal recessive mode of inheritance
Z. Al Lamki ,N. El Banna ,
Persistent neonatal hyperinsulinemic hypoglycemia [Nesidioblastosis]in two Omnii Siblings,
Saudi Med. J. 1993;
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