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  4. Pregnancy complications and neonatal outcomes in multiple pregnancies: a comparison between assisted reproductive techniques and spontaneous conception

Pregnancy complications and neonatal outcomes in multiple pregnancies: a comparison between assisted reproductive techniques and spontaneous conception

Authors

Kaveh Mahbod
Tehran University of Medical Science ; , School of Medicine ; , Paediatric Department ;

Int. J. Fertil. Steril. 2015; 8 (4): 367-372
IJFS-International Journal of Fertility and Sterility
Journal Country: Islamic Republic of Iran
P-ISSN: 2008-076X
E-ISSN: 2008-0778
Type of Publication: Journal Article
Category: Humans, Female,
Type of Research: Clinical
Keywords: Pregnancy, Multiple
Broad Subjects: Maternal, Reproductive and Child Health, Pregnancy ,Pregnancy Complications ,Infant, Newborn ,Pregnancy Outcome ,Reproductive Techniques, Assisted ,Fertilization ,Cross-Sectional Studies
Citation: Mahbod Kaveh , Pregnancy complications and neonatal outcomes in multiple pregnancies: a comparison between assisted reproductive techniques and spontaneous conception, Int. J. Fertil. Steril. 2015; 8 (4): 367-372

Abstract English

This study compared neonatal outcome and maternal complications in multiple pregnancies after assisted reproductive technologies [ART] to spontaneous pregnancies. In this cross-sectional study, we reviewed medical records of 190 multiple pregnancies and births conceived by ART or spontaneous conceptions between 2004 and 2009 in Women Hospital. Obstetric history and outcomes were recorded and compared between these two groups. SPSS version 13 was used for data analysis. The results were analyzed using student’s t test, chi square and logistic regression [p<0.05] . There were 106 deliveries from spontaneous conceptions and 84 that resulted from ART. Parity history and mode of delivery significantly differed between the two groups [p<0.001] . The ART group had significantly higher preterm labor and premature rupture of membranes [PROM] whereas pregnanc-induced hypertension [PIH] was higher in the spontaneous group [p=0.01] . Newborn intensive care unit [NICU] admission, duration of hospitalization, still birth and low gestational age were significantly higher in the ART group while neonatal jaundice was higher in the spontaneous group. Logistic regression analysis by considering neonatal complications as the dependent variable showed that respiratory distress syndrome [RDS] , NICU admission and Apgar score were independent predictors for neonatal complications. Obstetric and neonatal outcomes must be considered in multiple pregnancies conceived by ART

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